Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 17/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16906518 | 0.86 | EP300 (0.57) | EP300 | |
| SCHEMBL18079400 | 0.84 | EP300 (0.55) | EP300EPHX2 | |
| SCHEMBL16612622 | 0.81 | MAPK1 (0.46) | EP300 | |
| SCHEMBL22047628 | 0.81 | EPHX2 (0.45) | EP300EPHX2 | |
| SCHEMBL3739836 | 0.80 | EP300 (0.52) | EP300 | |
| SCHEMBL20617213 | 0.80 | EP300 (0.52) | EP300EPHX2CYP4F2CYP4A11 | |
| SCHEMBL17546708 | 0.79 | EP300 (0.51) | EP300 | |
| SCHEMBL12788075 | 0.78 | GBA1 (0.57) | EPHX2 | |
| SCHEMBL17104472 | 0.78 | EP300 (0.48) | EP300 | |
| SCHEMBL17104463 | 0.77 | EP300 (0.49) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829580-B2 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20060270706-A1 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1695962-A1 | CYCLIC AMINE DERIVATIVE HAVING HETEROARYL RING | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270706-A1 | Cyclic amine derivative having heteroaryl ring | F12, F2, H1-3 | EP300 618/4885EPHX2 690/4885CYP4F2 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.