SCHEMBL3734948

SCHEMBL3734948

Oc1c(N=Nc2nccs2)ccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.67
L3MBTL1 Q9Y468 7/20 0.67
MEN1 O00255 7/20 0.67
MAPT P10636 6/20 0.67
RAB9A P51151 5/20 0.67
KDM4E B2RXH2 4/20 0.67
NPSR1 Q6W5P4 4/20 0.67
TDP1 Q9NUW8 4/20 0.67
POLB P06746 3/20 0.67
HSP90AA1 P07900 3/20 0.67
MAPK1 P28482 2/20 0.67
RIOK2 Q9BVS4 2/20 0.67
PAX8 Q06710 1/20 0.67
KCNH2 Q12809 1/20 0.67
SMN1; SMN2 Q16637 3/20 0.59
LMNA P02545 2/20 0.59
OPRK1 P41145 2/20 0.59
HTT P42858 2/20 0.59
PKM P14618 1/20 0.59
IDO1 P14902 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3734946 1.00 KMT2A (0.67) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL18874941 0.82 KMT2A (0.61) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL28134113 0.82 KMT2A (0.61) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL27560322 0.82 KMT2A (0.56) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL30148047 0.80 MAPT (1.00) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL2732737 0.80 MAPT (1.00) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL2732741 0.80 MAPT (1.00) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL13646699 0.80 KMT2A (0.50) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL387565 0.79 KMT2A (0.73) KMT2AL3MBTL1MEN1MAPTRAB9A
SCHEMBL7554065 0.78 MAPT (0.78) KMT2AL3MBTL1MEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975613-B1 Kits and methods for evaluating hair damage OREAL (FR) 2012-07-18 EP disclosed
US-7749763-B2 Kits and methods for evaluating hair L'OREAL S.A. (FR) 2010-07-06 US disclosed
US-20080241854-A1 KITS AND METHODS FOR EVALUATING HAIR L'OREAL S.A. (FR) 2008-10-02 US disclosed
EP-1975613-A1 Kits and methods for evaluating hair L'OREAL (FR) 2008-10-01 EP disclosed