Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735321 | 1.00 | ALK (0.58) | ALK | |
| SCHEMBL676198 | 0.89 | ALK (0.66) | ALK | |
| SCHEMBL676199 | 0.89 | ALK (0.66) | ALK | |
| SCHEMBL676639 | 0.86 | ALK (0.56) | ALK | |
| SCHEMBL676640 | 0.86 | ALK (0.56) | ALK | |
| SCHEMBL676628 | 0.86 | ALK (0.45) | ALK | |
| SCHEMBL676627 | 0.86 | ALK (0.45) | ALK | |
| SCHEMBL676224 | 0.86 | ALK (0.47) | ALK | |
| SCHEMBL676225 | 0.86 | ALK (0.47) | ALK | |
| SCHEMBL675901 | 0.84 | ALK (0.50) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161271-A1 | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl | Università Degli Studi Di Milano - Bicocca (IT) | 2010-03-10 | — | — | EP | disclosed |