Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL11301479 | 0.88 | — | — | |
| Diethanolamine SCHEMBL23363665 | 0.88 | TSHR (0.36) | SMN1; SMN2TSHRL3MBTL1TP53ALOX15 | |
| Diethanolamine SCHEMBL8930798 | 0.88 | TSHR (0.36) | SMN1; SMN2TSHRL3MBTL1TP53ALOX15 | |
| Diethanolamine SCHEMBL5307430 | 0.88 | TSHR (0.36) | SMN1; SMN2TSHRL3MBTL1TP53ALOX15 | |
| Diethanolamine SCHEMBL5843119 | 0.88 | — | — | |
| Diethanolamine SCHEMBL2324 | 0.88 | — | — | |
| Diethanolamine SCHEMBL7893791 | 0.84 | — | — | |
| Diethanolamine SCHEMBL11150361 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRL3MBTL1TP53ALOX15 | |
| SCHEMBL10892467 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRL3MBTL1TP53ALOX15 | |
| Diethanolamine SCHEMBL9448589 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336960-A | Novel environmentally friendly degreasing agent | 魏忠 | 2017-01-18 | — | — | CN | claimed |
| US-7833638-B2 | laminate comprised of first layer and second layer, first layer being selected from a gypsum board, an insulation wallboard, a polyisocyanurate foam board, and a ceiling tile, and second layer being a glass mat comprised of glass fibers and a coating comprised of a silicate binder; fire resistance | JOHNS MANVILLE (US) | 2010-11-16 | — | — | US | claimed |
| US-20090155603-A1 | Glass mat with inorganic coating | JOHNS MANVILLE | 2009-06-18 | — | — | US | claimed |
| US-20240003033-A1 | COMPOUND DISPERSANT AND PREPARATION METHOD, AND MIXED ELECTROPLATING SOLUTION AND PREPARATION METHOD | ZHEJIANG CHINT ELECTRICS CO.,LTD. (CN) | 2024-01-04 | — | — | US | disclosed |
| EP-4227443-A1 | COMPOUND DISPERSANT AND PREPARATION METHOD, AND MIXED ELECTROPLATING SOLUTION AND PREPARATION METHOD | Zhejiang Chint Electrics Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-115182017-A | Compound dispersant and preparation method thereof, and mixed electroplating solution and preparation method thereof | 浙江正泰电器股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-106336960-A | Novel environmentally friendly degreasing agent | 魏忠 | 2017-01-18 | — | — | CN | disclosed |
| CN-106336960-A | Novel environmentally friendly degreasing agent | 魏忠 | 2017-01-18 | — | — | CN | disclosed |