SCHEMBL373817

SCHEMBL373817

OC(CBr)COCC(O)CBr

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.35
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
HSD17B10 Q99714 1/20 0.32
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11913779 0.89 USP2 (0.43) KDM4EALDH1A1USP2
SCHEMBL12516729 0.83
SCHEMBL18974122 0.83
SCHEMBL18973995 0.83
SCHEMBL10316172 0.83 KDM4E (0.35) KDM4E
SCHEMBL23059684 0.81 KDM4E (0.34) KDM4EHSD17B10
SCHEMBL23018483 0.79 HSD17B10 (0.35) KDM4EHSD17B10
SCHEMBL17769278 0.79
SCHEMBL14861151 0.77 MEN1 (0.50) ALDH1A1HSD17B10USP2
SCHEMBL9185093 0.75 USP2 (0.57) KDM4EALDH1A1HSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2410016-B1 Brominated polymers as flame retardant additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-09-11 EP claimed
CN-101959954-B Brominated polymers as flame retardant additives and polymer systems containing the same DOW GLOBAL TECHNOLOGIES INC (US) 2013-03-27 CN claimed
CN-102936382-A Brominated polymers as flame additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES INC (US) 2013-02-20 CN claimed
CN-102850718-A Brominated Polymers as FR Additives and Polymer Systems Containing Same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-02 CN claimed
US-8242183-B2 Brominated polymers as FR additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2012-08-14 US claimed
EP-2410016-A2 Brominated polymers as flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-01-25 EP claimed
EP-2410014-A2 Brominated polymers as flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-01-25 EP claimed
EP-2410015-A2 Brominated polymers as flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-01-25 EP claimed
JP-2011513537-A 2011-04-28 JP claimed
CN-101959954-A Brominated polymers as flame retardant additives and polymer systems containing the same DOW GLOBAL TECHNOLOGIES INC (US) 2011-01-26 CN claimed
US-20100317757-A1 Brominated Polymers as FR Additives and Polymer Systems Containing Same THE DOW CHEMICAL COMPANY 2010-12-16 US claimed
EP-2247664-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME Dow Global Technologies Inc. (US) 2010-11-10 EP claimed
WO-2009108453-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-09-03 WO claimed
US-10662380-B2 Vinyl polymers having a flame-retardant function VERSALIS S.P.A. (IT) 2020-05-26 US disclosed
EP-3122792-B1 VINYL POLYMERS HAVING A FLAME-RETARDANT FUNCTION VERSALIS SPA (IT) 2018-10-17 EP disclosed
US-20170051209-A1 VINYL POLYMERS HAVING A FLAME-RETARDANT FUNCTION VERSALIS S.P.A. (IT) 2017-02-23 US disclosed
EP-2247664-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME Dow Global Technologies Inc. (US) 2010-11-10 EP disclosed
EP-2247664-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME Dow Global Technologies Inc. (US) 2010-11-10 EP disclosed
WO-2009108453-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-09-03 WO disclosed
WO-2009108453-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-09-03 WO disclosed