Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.69 |
| ▸ | ACP1 | P24666 | 13/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588994 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL23015135 | 0.82 | ACP1 (0.73) | SYKACP1 | |
| SCHEMBL29636689 | 0.82 | ACP1 (0.73) | SYKACP1 | |
| SCHEMBL29636697 | 0.78 | ACP1 (0.68) | SYKACP1 | |
| SCHEMBL23015121 | 0.78 | ACP1 (0.68) | SYKACP1 | |
| Hydrochloric Acid SCHEMBL23015090 | 0.78 | ACP1 (0.67) | SYKACP1 | |
| Hydrochloric Acid SCHEMBL29636794 | 0.78 | ACP1 (0.67) | SYKACP1 | |
| SCHEMBL23015208 | 0.75 | ACP1 (0.63) | SYKACP1 | |
| SCHEMBL23029741 | 0.75 | SYK (0.62) | SYKACP1 | |
| SCHEMBL29874547 | 0.75 | SYK (0.62) | SYKACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215092-B1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |