Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.57 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100644 | 0.89 | TYR (0.62) | TYRSLC5A2SLC28A3HIF1AMEN1 | |
| SCHEMBL5506137 | 0.89 | TYR (0.62) | TYRSLC5A2SLC28A3HIF1AMEN1 | |
| SCHEMBL23479758 | 0.89 | TYR (0.62) | TYRSLC5A2SLC28A3HIF1AMEN1 | |
| SCHEMBL14120978 | 0.89 | TYR (0.62) | TYRSLC5A2SLC28A3HIF1AMEN1 | |
| SCHEMBL26355898 | 0.85 | TYR (0.61) | TYRSLC5A2SLC28A3EPHX2 | |
| SCHEMBL4367622 | 0.83 | SLC28A3 (0.70) | TYRSLC5A2SLC28A3HIF1AMEN1 | |
| SCHEMBL23031052 | 0.83 | SLC28A3 (0.70) | TYRSLC5A2SLC28A3HIF1AMEN1 | |
| SCHEMBL23480032 | 0.81 | SLC5A2 (0.68) | TYRSLC5A2SLC28A3MEN1KMT2A | |
| SCHEMBL23479692 | 0.81 | SLC5A2 (0.68) | TYRSLC5A2SLC28A3MEN1KMT2A | |
| SCHEMBL28789347 | 0.81 | SLC5A2 (0.68) | TYRSLC5A2SLC28A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795302-B2 | Use of compositions for treating rosacea | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-09-14 | — | — | US | disclosed |
| US-20080070874-A1 | using retinoid or tetracycline as bactericide, benzoyl peroxide as metalloproteinases (MMPs) and neutrophil elastase inhibitors; antiscarring agents; reduction in procollagen biosynthesis | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2008-03-20 | — | — | US | disclosed |
| US-7268148-B2 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-09-11 | — | — | US | disclosed |
| US-7078048-B2 | Method and compositions for treating rosacea | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-07-18 | — | — | US | disclosed |
| US-20060078582-A1 | Use of compositions for treating rosacea | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2006-04-13 | — | — | US | disclosed |
| EP-1385496-A4 | USE OF COMPOSITIONS FOR TREATING ROSACEA | UNIV MICHIGAN (US) | 2006-03-29 | — | — | EP | disclosed |
| US-20060009494-A1 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | VOORHEES JOHN J | 2006-01-12 | — | — | US | disclosed |
| US-20050277695-A1 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | VOORHEES JOHN J | 2005-12-15 | — | — | US | disclosed |
| US-20040235950-A1 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2004-11-25 | — | — | US | disclosed |
| EP-1385496-A2 | USE OF COMPOSITIONS FOR TREATING ROSACEA | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1284721-A2 | COMPOSITIONS AND METHODS FOR USE AGAINST ACNE-INDUCED INFLAMMATION AND DERMAL MATRIX-DEGRADING ENZYMES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2003-02-26 | — | — | EP | disclosed |
| US-20020183399-A1 | Method and compositions for treating rosacea | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2002-12-05 | — | — | US | disclosed |
| WO-2002089743-A2 | USE OF COMPOSITIONS FOR TREATING ROSACEA | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2001089502-A2 | COMPOSITIONS AND METHODS FOR USE AGAINST ACNE-INDUCED INFLAMMATION AND DERMAL MATRIX-DEGRADING ENZYMES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-11-29 | — | — | WO | disclosed |