Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3742853 | 0.99 | KDR (0.43) | KDRCHEK1CYP2D6PDGFRBPDGFRA | |
| SCHEMBL3735598 | 0.85 | DAO (0.35) | CYP2D6MAOBMOGAT2CYP2C9CYP3A4 | |
| SCHEMBL3738420 | 0.84 | MOGAT2 (0.35) | CYP2D6MAOBMOGAT2CYP2C9CYP3A4 | |
| SCHEMBL3742722 | 0.84 | MOGAT2 (0.35) | CYP2D6MAOBMOGAT2CYP2C9CYP3A4 | |
| SCHEMBL3741631 | 0.84 | MOGAT2 (0.35) | CYP2D6MAOBMOGAT2CYP2C9CYP3A4 | |
| SCHEMBL3745791 | 0.84 | MOGAT2 (0.35) | CYP2D6MAOBMOGAT2CYP2C9CYP3A4 | |
| SCHEMBL3745629 | 0.82 | MAOB (0.38) | CYP2D6MAOBMOGAT2CYP2C9 | |
| SCHEMBL3738040 | 0.81 | GRIA1 (0.39) | CYP2D6CTSVCTSLMAOBALDH1A1 | |
| SCHEMBL3750862 | 0.78 | KDR (0.40) | KDRCHEK1CYP2D6PDGFRBPDGFRA | |
| SCHEMBL3741483 | 0.77 | DAO (0.34) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |