Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.66 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731589 | 0.95 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1 | |
| SCHEMBL3125115 | 0.93 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1 | |
| SCHEMBL3532107 | 0.89 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL13080863 | 0.88 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL3123905 | 0.86 | HSP90AA1 (0.87) | HSP90AA1HSP90AB1 | |
| SCHEMBL3125177 | 0.86 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1 | |
| SCHEMBL3537857 | 0.85 | HSP90AA1 (0.70) | HSP90AA1HSP90AB1 | |
| SCHEMBL13731242 | 0.85 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1 | |
| SCHEMBL3525878 | 0.84 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL3124014 | 0.82 | HSP90AA1 (0.82) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012148550-A1 | PRODRUGS OF THERAPEUTIC COMPOUNDS | MYREXIS, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| US-20100292255-A1 | Therapeutic Compounds and Their Use in Treating Diseases and Disorders | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292255-A1 | Therapeutic Compounds and Their Use in Treating Diseases and Disorders | VHL, CLN6, CFTR | HSP90AA1 659/4885HSP90AB1 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.