Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20626388 | 0.81 | SLC29A1 (0.76) | SLC29A1ADORA2AADORA2BTP53ALDH1A1 | |
| SCHEMBL20626389 | 0.81 | SLC29A1 (0.76) | SLC29A1ADORA2AADORA2BTP53ALDH1A1 | |
| SCHEMBL14713425 | 0.81 | SLC29A1 (0.76) | SLC29A1ADORA2AADORA2BTP53ALDH1A1 | |
| SCHEMBL14714055 | 0.81 | SLC29A1 (0.76) | SLC29A1ADORA2AADORA2BTP53ALDH1A1 | |
| SCHEMBL7744330 | 0.81 | SLC29A1 (0.76) | SLC29A1ADORA2AADORA2BTP53ALDH1A1 | |
| SCHEMBL3437083 | 0.77 | PRMT5 (0.48) | SLC29A1ADORA2AADORA2BPOLBMAPK1 | |
| SCHEMBL3437082 | 0.77 | PRMT5 (0.48) | SLC29A1ADORA2AADORA2BPOLBMAPK1 | |
| SCHEMBL14946260 | 0.76 | PRMT5 (0.65) | SLC29A1ADORA2AADORA2BPOLBMAPK1 | |
| SCHEMBL14853754 | 0.76 | PRMT5 (0.65) | SLC29A1ADORA2AADORA2BPOLBMAPK1 | |
| SCHEMBL3436912 | 0.76 | PRMT5 (0.65) | SLC29A1ADORA2AADORA2BPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825102-B2 | Treatment of dry eye conditions | CAN-FITE BIOPHARMA LTD. (IL) | 2010-11-02 | — | — | US | claimed |