Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.72 |
| ▸ | TXK | P42681 | 1/20 | 0.68 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.68 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772545 | 0.84 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373985 | 0.82 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373973 | 0.82 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373922 | 0.81 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL374047 | 0.81 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373569 | 0.81 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373791 | 0.80 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL27764191 | 0.80 | SYK (0.80) | SYKTXKKARS1SLK | |
| SCHEMBL590059 | 0.77 | SYK (0.65) | SYKTXKKARS1SLK | |
| SCHEMBL373950 | 0.76 | SYK (0.69) | SYKTXKKARS1SLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215092-B1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |