Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.60 |
| ▸ | TOP2A | P11388 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | PTGES | O14684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NT5E | P21589 | 3/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GLI1 | P08151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953264 | 0.83 | PTPN1 (0.46) | PTPN1TOP2ACES2CES1PTGES | |
| SCHEMBL18668382 | 0.82 | GPBAR1 (0.46) | PTPN1TOP2ACES2CES1PTGES | |
| Lupenone SCHEMBL27218586 | 0.81 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1PTGES | |
| Lupenone SCHEMBL13692854 | 0.81 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1PTGES | |
| Lupenone SCHEMBL13908727 | 0.81 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1PTGES | |
| Lupenone SCHEMBL13908802 | 0.81 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1PTGES | |
| Lupenone SCHEMBL13851777 | 0.81 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1PTGES | |
| Lupenone SCHEMBL1224027 | 0.81 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1PTGES | |
| Glochidiol SCHEMBL31237879 | 0.81 | PTPN1 (0.71) | PTPN1TOP2ACES2CES1PTGES | |
| SCHEMBL17124246 | 0.78 | PTPN1 (0.63) | PTPN1TOP2ACES2CES1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104274831-A | Composition based on naturally derived peptide and inflammation inhibitor and/or anti-oxidation compound | SOO TUCK POOI | 2015-01-14 | — | — | CN | claimed |
| CN-104274831-A | Composition based on naturally derived peptide and inflammation inhibitor and/or anti-oxidation compound | SOO TUCK POOI | 2015-01-14 | — | — | CN | disclosed |
| EP-1395270-B1 | USE OF PHYLLANTHUS COMPONENTS FOR PREPARATION OF A MEDICAMENT FOR THE PREVENTION OR TREATMENT OF INFECTIONS CAUSED BY RESISTANT HEPATITIS B VIRUS | PHYTRIX AG (DE) | 2014-07-23 | — | — | EP | disclosed |
| US-7829124-B2 | Use of Phyllanthus constituents for treating or preventing infections caused by hepatitis B-viruses | OTT MICHAEL | 2010-11-09 | — | — | US | disclosed |
| US-20070264359-A1 | administering an effective amount of an aqueous or alcohol extract of Phyllanthus to a mammal infected with the YMDD hepatitis B virus mutant strain resistant; inhibiting viral gene expression in a mammal infected with a hepatitis B virus | OTT MICHEAL | 2007-11-15 | — | — | US | disclosed |
| US-20040197426-A1 | inhibition of the amplification of a hepatitis B virus resistant to nucleoside analogues (Lamivudine and Famciclovir) | OTT MICHAEL (DE) | 2004-10-07 | — | — | US | disclosed |
| EP-1395270-A1 | USE OF PHYLLANTHUS CONSTITUENTS FOR TREATING OR PREVENTING INFECTIONS CAUSED BY HEPATIT | Phytrix AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| US-20040028754-A1 | Use of phyllanthus component for the treatment or prophylaxis of infections triggered by flaviviridae | VON KEUDELL CHRISTOPH (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-1294387-A2 | USE OF PHYLLANTHUS CONSTITUENTS FOR TREATING OR PREVENTING INFECTIONS CAUSED BY FLAVIVIRIDAE | CMI-Centers for Medical Innovation AG (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002087600-A1 | USE OF PHYLLANTHUS CONSTITUENTS FOR TREATING OR PREVENTING INFECTIONS CAUSED BY HEPATIT | PHYTRIX AG (DE) | 2002-11-07 | — | — | WO | disclosed |
| US-20020054921-A1 | The extract form the plant genus Phyllanthus belongs to the subfamily of Phyllantoideae which belong to the family of Euphoribiaceae, contacted to the viruses belonging to the family of Flaviviridae | CMI CENTERS FOR MEDICAL INOVATION AG (DE) | 2002-05-09 | — | — | US | disclosed |
| WO-2001097824-A2 | USE OF PHYLLANTHUS CONSTITUENTS FOR TREATING OR PREVENTING INFECTIONS CAUSED BY FLAVIVIRIDAE | CMI-CENTERS FOR MEDICAL INNOVATION AG (DE) | 2001-12-27 | — | — | WO | disclosed |