Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 10/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16209660 | 0.85 | KMT2A (0.78) | KCNA5GAAKDM4EMAPTMAPK1 | |
| SCHEMBL2879685 | 0.79 | KCNA5 (0.71) | KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL2884137 | 0.78 | KCNA5 (0.70) | KCNA5KCNH2 | |
| SCHEMBL2885524 | 0.77 | KCNA5 (0.63) | KCNA5GAAKDM4EMAPTMAPK1 | |
| SCHEMBL2882881 | 0.76 | KCNA5 (0.62) | KCNA5GAAKDM4EMAPTMAPK1 | |
| SCHEMBL2879683 | 0.75 | KCNA5 (0.64) | KCNA5GAAKDM4EMAPTMAPK1 | |
| SCHEMBL2882065 | 0.75 | KCNA5 (0.69) | KCNA5KCNH2 | |
| SCHEMBL2879798 | 0.74 | KCNA5 (0.73) | KCNA5KCNH2 | |
| SCHEMBL2884600 | 0.74 | KCNA5 (0.73) | KCNA5KCNH2 | |
| SCHEMBL2884261 | 0.74 | KCNA5 (1.00) | KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833805-B2 | Selectively permeable membranes on porous substrates | UNIVERSITY OF CINCINNATI (US) | 2010-11-16 | — | — | US | claimed |
| US-7833805-B2 | Selectively permeable membranes on porous substrates | UNIVERSITY OF CINCINNATI (US) | 2010-11-16 | — | — | US | disclosed |
| US-20070116610-A1 | Selectively permeable membranes on porous substrates | CUPPOLETTI JOHN | 2007-05-24 | — | — | US | disclosed |
| WO-2006047323-A2 | SELECTIVELY PERMEABLE MEMBRANES ON POROUS SUBSTRATES | UNIVERSITY OF CINCINNATI (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060068503-A1 | Solid support membranes for ion channel arrays and sensors: application ro rapid screening of pharmacological compounds | CUPPOLETTI JOHN | 2006-03-30 | — | — | US | disclosed |