Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28521562 | 0.98 | KDM4E (0.65) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL10685190 | 0.89 | KDM4E (0.64) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL28516422 | 0.87 | KDM4E (0.66) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL2403602 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL2404387 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL2460856 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL2389653 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL17102841 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL28786423 | 0.84 | OXER1 (0.60) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL28518839 | 0.83 | EGFR (0.66) | KDM4EALDH1A1GAAMAPTCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210348139-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-11-11 | — | — | US | disclosed |
| CN-107698658-B | Bis [3- (acetyl-Lys-AA-OBzl) -indol-2-yl ] ethane, preparation, activity and application thereof | 首都医科大学 | 2021-02-12 | — | — | CN | disclosed |
| US-20200123512-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-04-23 | — | — | US | disclosed |
| US-10544402-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS INC. (US) | 2020-01-28 | — | — | US | disclosed |
| EP-2828385-B1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | CODEXIS INC (US) | 2018-02-07 | — | — | EP | disclosed |
| US-20170283781-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-10-05 | — | — | US | disclosed |
| US-9708588-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160289649-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-10-06 | — | — | US | disclosed |
| US-9388395-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150344854-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-12-03 | — | — | US | disclosed |
| EP-2657705-A2 | Biomarkers for prostate cancer and methods using the same | Metabolon Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2013142770-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | CODEXIS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| US-8518650-B2 | Biomarkers for prostate cancer and methods using the same | METABOLON, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2560006-A2 | Biomarkers for prostate cancer and methods using the same | Metabolon Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2061899-B1 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | METABOLON INC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20100292331-A1 | Biomarkers for Prostate Cancer and Methods Using the Same | METABALON, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20070298998-A1 | Biomarkers for amyotrophic lateral sclerosis and methods using the same | METABOLON, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | KDM4E 2972/4885ALDH1A1 2042/4885GAA 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.