Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.60 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.58 |
| ▸ | MARK3 | P27448 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 17/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969630 | 1.00 | MAP4K4 (0.60) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1969626 | 1.00 | MAP4K4 (0.60) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1967809 | 0.90 | MAP4K4 (0.56) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1967806 | 0.90 | MAP4K4 (0.56) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1967804 | 0.90 | MAP4K4 (0.56) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1969686 | 0.85 | MAP4K4 (0.60) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL3746333 | 0.83 | MAP4K4 (0.63) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL3741171 | 0.82 | MAP4K4 (0.65) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL3741047 | 0.82 | S1PR1 (0.73) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL12450219 | 0.81 | MAP4K4 (0.62) | MAP4K4MINK1DYRK3MARK3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | claimed |