⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477646 | 0.69 | — | — | |
| SCHEMBL1856117 | 0.67 | — | — | |
| SCHEMBL31649405 | 0.67 | — | — | |
| SCHEMBL122103 | 0.67 | — | — | |
| Bromide SCHEMBL2745855 | 0.65 | — | — | |
| SCHEMBL31092010 | 0.65 | — | — | |
| SCHEMBL10898470 | 0.63 | — | — | |
| Cyclopropane SCHEMBL665011 | 0.62 | — | — | |
| SCHEMBL13817748 | 0.62 | — | — | |
| SCHEMBL7341958 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560932-B1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES OF SAME | JAPAN TOBACCO INC (JP) | 2026-03-11 | — | — | EP | disclosed |
| US-20250084106-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF | LEO PHARMA A/S (DK) | 2025-03-13 | — | — | US | disclosed |
| US-12195481-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAPAN TOBACCO INC. (JP) | 2025-01-14 | — | — | US | disclosed |
| US-20240140967-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF | LEO PHARMA A/S (DK) | 2024-05-02 | — | — | US | disclosed |
| CN-117865992-A | Process for preparing 7H-pyrrolo [2,3-d ] pyrimidine derivatives and synthetic intermediates therefor | 日本烟草产业株式会社 | 2024-04-12 | — | — | CN | disclosed |
| CN-113957004-B | Flavobacterium aureum and application thereof in preparation of halophyte epiphyte repair maintenance microbial inoculum | 中国科学院烟台海岸带研究所 | 2024-02-20 | — | — | CN | disclosed |
| CN-114615890-B | Herbicidal mixtures comprising aminopyridine and quinic acid | 安道麦阿甘有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-110300756-B | Process for preparing 7H-pyrrolo [2,3-d ] pyrimidine derivatives and synthetic intermediates therefor | 日本烟草产业株式会社 | 2024-01-02 | — | — | CN | disclosed |
| CN-112236421-B | Pyrazole derivatives and pest control agents | 组合化学工业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| CN-110505874-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2023-09-26 | — | — | CN | disclosed |
| US-7005438-B2 | Pharmaceutically active isoindoline derivatives | CELGENE CORPORATION (US) | 2006-02-28 | — | — | US | disclosed |
| US-6762195-B2 | TREATING DISEASES MEDIATED BY TUMOR NECROSIS FACTOR; INHIBIT ANGIOGENESIS AND TREATMENT OF CANCER, INFLAMMATORY, AND AUTOIMMUNE DISEASES | CELGENE CORPORATION | 2004-07-13 | — | — | US | disclosed |
| US-20040122052-A1 | Pharmaceutically active isoindoline derivatives | CELGENE CORPORATION | 2004-06-24 | — | — | US | disclosed |
| EP-1341537-A4 | PHARMACEUTICALLY ACTIVE ISOINDOLINE DERIVATIVES | CELGENE CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1341537-A2 | PHARMACEUTICALLY ACTIVE ISOINDOLINE DERIVATIVES | CELGENE CORPORATION (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20030069428-A1 | Pharmaceutically active isoindoline derivatives | MULLER GEORGE | 2003-04-10 | — | — | US | disclosed |
| WO-2002094180-A2 | PHARMACEUTICALLY ACTIVE ISOINDOLINE DERIVATIVES | CELGENE CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |
| US-6458810-B1 | TREATMENT OF DISEASE STATES MEDIATED BY, TNF.ALPHA.. A TYPICAL EMBODIMENT IS TUMOR NECROSIS FACTOR FOR CANCER TREATMENT | CELGENE CORPORATION | 2002-10-01 | — | — | US | disclosed |
| EP-1086064-A2 | DIRECTED COMBINATORIAL COMPOUND LIBRARY AND HIGH THROUGHPUT ASSAYS FOR SCREENING SAME | Glycodesign Inc. (CA) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064378-A2 | DIRECTED COMBINATORIAL COMPOUND LIBRARY AND HIGH THROUGHPUT ASSAYS FOR SCREENING SAME | GLYCODESIGN INC. (CA) | 1999-12-16 | — | — | WO | disclosed |