SCHEMBL3745281

SCHEMBL3745281

CCC(CC)COC(=O)CCC(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
CYP3A4 P08684 1/20 0.55
ATM Q13315 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 4/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
RECQL P46063 1/20 0.38
DUSP3 P51452 1/20 0.37
CA12 O43570 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3740753 0.92 TSHR (0.66) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3756095 0.92 TSHR (0.61) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3740920 0.91 TSHR (0.62) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3745851 0.90 TSHR (0.64) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3743400 0.90 TSHR (0.64) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3757496 0.90 TSHR (0.64) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3753740 0.90 TSHR (0.64) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3753510 0.90 TSHR (0.64) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL3753822 0.90 TSHR (0.64) TSHRCYP3A4ATMTDP1KMT2A
SCHEMBL27559533 0.85 TSHR (0.56) TSHRCYP3A4ATMTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079850-B2 Cosmetic compositions containing esters of 2-ethylbutanol COGNIS IP MANAGEMENT GMBH (DE) 2015-07-14 US disclosed
US-20100292328-A1 Cosmetic Compositions Containing Esters of 2-ethylbutanol COGNIS IP MANAGEMENT GMBH (DE) 2010-11-18 US disclosed