Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.62 |
| ▸ | CNR2 | P34972 | 12/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746051 | 1.00 | CNR1 (0.62) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3749845 | 0.91 | CNR1 (0.58) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3749842 | 0.91 | CNR1 (0.58) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3740079 | 0.90 | CNR1 (0.64) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3740069 | 0.90 | CNR1 (0.64) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3744163 | 0.90 | CNR1 (0.64) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3744169 | 0.90 | CNR1 (0.64) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3741225 | 0.89 | CNR1 (0.63) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3741230 | 0.89 | CNR1 (0.63) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL3749835 | 0.87 | CNR1 (0.65) | CNR1CNR2OPRL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834046-B2 | Thiophene compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-11-16 | — | — | US | disclosed |
| US-20090029969-A2 | Thiophene Compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-01-29 | — | — | US | disclosed |
| US-20080090810-A1 | THIOPHENE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090810-A1 | THIOPHENE COMPOUNDS | CNR1, CNR2, HTR2C | CNR1 1/4885CNR2 2/4885OPRL1 4/4885 |
| US-20090029969-A2 | Thiophene Compounds | CNR1, CNR2, HTR2C | CNR1 1/4885CNR2 2/4885OPRL1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.