SCHEMBL374674

SCHEMBL374674

[C]1[C]=CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1474 0.69
SCHEMBL14937506 0.59
SCHEMBL102953 0.49
SCHEMBL374036 0.46
SCHEMBL321677 0.46
SCHEMBL2718753 0.46
SCHEMBL1178 0.42
Hydrochloric Acid SCHEMBL4026914 0.39
Hydrochloric Acid SCHEMBL552 0.39
Hydrochloric Acid SCHEMBL21351719 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894107-B1 COMPOUNDS WITH SPIRO ATOMS AND THEIR USE AS ELECTROLUMINESCENT MATERIALS AVENTIS RES & TECH GMBH & CO (DE) 1999-12-22 EP claimed
EP-3853237-B1 PHOSPHONATE-CONTAINING CROSSLINKERS UNIV UTRECHT HOLDING BV (NL) 2024-04-24 EP disclosed
EP-3853237-A1 PHOSPHONATE-CONTAINING CROSSLINKERS Universiteit Utrecht Holding B.V. (NL) 2021-07-28 EP disclosed
WO-2020060412-A1 PHOSPHONATE-CONTAINING CROSSLINKERS UNIVERSITEIT UTRECHT HOLDING B.V. (NL) 2020-03-26 WO disclosed
US-9040221-B2 Radiation-sensitive resin composition, method for forming resist pattern, and polymer and compound JSR CORPORATION (JP) 2015-05-26 US disclosed
US-20130122426-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, AND POLYMER AND COMPOUND JSR CORPORATION (JP) 2013-05-16 US disclosed
US-20130012430-A1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-01-10 US disclosed
US-8314141-B2 Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-11-20 US disclosed
EP-2409985-A2 Inhibitors de serine proteases, especially of the NS3 protease of the hepatitis C virus VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-01-25 EP disclosed
US-20110112114-A1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-05-12 US disclosed
US-6608067-B1 Treating hepatitis C viral infection VERTEX PHARMACEUTICALS INCORPORATED 2003-08-19 US disclosed
US-20020032175-A1 Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease VERTEX PHARMACEUTICALS INCORPORATED 2002-03-14 US disclosed
EP-0932617-B1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE VERTEX PHARMA (US) 2002-01-16 EP disclosed
EP-1136498-A1 Inhibitors of serine proteases, particularly hepatitis c virus NS3 protease Vertex Pharmaceuticals Incorporated (US) 2001-09-26 EP disclosed
US-6265380-B1 Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease VERTEX PHARMACEUTICALS INCORPORATED 2001-07-24 US disclosed
EP-1066247-A1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE Vertex Pharmaceuticals Incorporated (US) 2001-01-10 EP disclosed
WO-1999050230-A1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1999-10-07 WO disclosed
EP-0932617-A1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE Vertex Pharmaceuticals Incorporated (US) 1999-08-04 EP disclosed
US-5763636-A CONJUGATED POLYCYCLIC POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed
WO-1998017679-A1 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-04-30 WO disclosed