Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748816 | 1.00 | ESR2 (0.45) | ESR2 | |
| SCHEMBL3012886 | 0.77 | — | — | |
| SCHEMBL8660901 | 0.76 | ESR2 (0.47) | ESR2 | |
| SCHEMBL12385989 | 0.74 | ESR2 (0.50) | ESR2 | |
| SCHEMBL12528053 | 0.74 | ESR2 (0.45) | ESR2 | |
| SCHEMBL3112772 | 0.74 | ESR2 (0.45) | ESR2 | |
| SCHEMBL3748819 | 0.74 | ESR2 (0.50) | ESR2 | |
| SCHEMBL13240744 | 0.74 | ESR2 (0.45) | ESR2 | |
| SCHEMBL12525042 | 0.74 | ESR2 (0.45) | ESR2 | |
| SCHEMBL12424446 | 0.74 | ESR2 (0.50) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185537-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | Pfizer Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |