Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 13/20 | 0.46 |
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL3282266 | 0.93 | KDM4E (0.53) | KDM4EMEN1MAPTMAPK1KMT2A | |
| SCHEMBL3743034 | 0.90 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL3754418 | 0.87 | KDM4E (0.51) | KDM4EMEN1MAPTMAPK1KMT2A | |
| Cyclopentane SCHEMBL3281526 | 0.82 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL3294631 | 0.76 | KDM4E (0.52) | KDM4EMEN1MAPTMAPK1KMT2A | |
| SCHEMBL3744077 | 0.76 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL3735382 | 0.75 | KDM4E (0.49) | KDM4EMEN1MAPTMAPK1KMT2A | |
| SCHEMBL3735383 | 0.74 | CNR2 (0.50) | KDM4EMEN1MAPTMAPK1KMT2A | |
| SCHEMBL16161240 | 0.74 | KDM4E (0.49) | KDM4EMEN1MAPTMAPK1KMT2A | |
| SCHEMBL3280613 | 0.74 | CNR2 (0.64) | KDM4EMEN1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068870-B1 | THIOPHENE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2013-03-27 | — | — | EP | disclosed |
| US-7834046-B2 | Thiophene compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-11-16 | — | — | US | disclosed |
| CN-101535260-A | Thiophene compounds | NAT HEALTH RESEARCH INSTITUTES (CN) | 2009-09-16 | — | — | CN | disclosed |
| US-20090029969-A2 | Thiophene Compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-01-29 | — | — | US | disclosed |
| US-20080090810-A1 | THIOPHENE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090810-A1 | THIOPHENE COMPOUNDS | CNR1, CNR2, HTR2C | KDM4E 1205/4885MEN1 2402/4885MAPT 1046/4885 |
| US-20090029969-A2 | Thiophene Compounds | CNR1, CNR2, HTR2C | KDM4E 1205/4885MEN1 2402/4885MAPT 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.