Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.67 |
| ▸ | KDR | P35968 | 5/20 | 0.62 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | INSR | P06213 | 1/20 | 0.62 |
| ▸ | FBP1 | P09467 | 1/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.62 |
| ▸ | FLT4 | P35916 | 1/20 | 0.62 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | TEK | Q02763 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.62 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276159 | 1.00 | EGFR (0.67) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL209803 | 0.96 | EGFR (0.72) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL119490 | 0.96 | EGFR (0.72) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL29623629 | 0.96 | EGFR (0.72) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL1446203 | 0.96 | EGFR (0.72) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL29623406 | 0.91 | EGFR (0.79) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL121215 | 0.91 | EGFR (0.79) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL1446479 | 0.91 | EGFR (0.79) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL209526 | 0.91 | EGFR (0.79) | EGFRKDREPHB4ERBB2AURKA | |
| SCHEMBL208447 | 0.88 | EGFR (0.70) | EGFRKDREPHB4ERBB2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408500-A1 | DISPENSING DEVICE, STORAGE DEVICE AND METHOD FOR DISPENSING A FORMULATION | Boehringer Ingelheim International GmbH (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2009153049-A1 | INHALER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-23 | — | — | WO | disclosed |