Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.78 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.61 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL17184327 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL4394463 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL4401591 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL466382 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL28161805 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL17184328 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| D-Leucine SCHEMBL11768667 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL11305893 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL466383 | 1.00 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL2553000 | 0.96 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408462-A1 | Targeted delivery of chemotherapeutic agents | Sanford-Burnham Medical Research Institute (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108122-A1 | TARGETED DELIVERY OF CHEMOTHERAPEUTIC AGENTS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2010-09-23 | — | — | WO | disclosed |