Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 11/20 | 0.78 |
| ▸ | GUSB | P08236 | 2/20 | 0.65 |
| ▸ | GLB1 | P16278 | 1/20 | 0.58 |
| ▸ | GBA2 | Q9HCG7 | 10/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713123 | 0.89 | GBA1 (0.97) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL5328837 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL8182808 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL2715246 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL8182126 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL8182197 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL8186655 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL8181038 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL8181310 | 0.88 | GBA1 (1.00) | GBA1GUSBGLB1GBA2GAA | |
| SCHEMBL13032182 | 0.86 | GBA1 (0.79) | GBA1GUSBGLB1GBA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173738-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF VIRAL INFECTIONS AND METHODS FOR PREPARING THEM | Nanodream S.r.l. Unipersonale (IT) | 2010-04-14 | — | — | EP | claimed |
| WO-2008101514-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF VIRAL INFECTIONS AND METHODS FOR PREPARING THEM | NANODREAM S.R.L. UNIPERSONALE (IT) | 2008-08-28 | — | — | WO | claimed |
| EP-2173738-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF VIRAL INFECTIONS AND METHODS FOR PREPARING THEM | Nanodream S.r.l. Unipersonale (IT) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008101514-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF VIRAL INFECTIONS AND METHODS FOR PREPARING THEM | NANODREAM S.R.L. UNIPERSONALE (IT) | 2008-08-28 | — | — | WO | disclosed |