SCHEMBL3756289

SCHEMBL3756289

NC(O)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17130433 1.00
SCHEMBL2331929 0.72
SCHEMBL2670774 0.72
SCHEMBL25015439 0.72
SCHEMBL14941333 0.72
SCHEMBL652954 0.70
SCHEMBL1613708 0.70
Formic Acid SCHEMBL3667111 0.70
SCHEMBL118667 0.70
SCHEMBL1570079 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108395413-B A kind of preparation method of morpholine -3- carboxylic acid 上海馨远医药科技有限公司 2019-05-28 CN claimed
CN-101675053-B Phosphoinositide 3-kinase inhibitor compounds and methods of use GENENTECH INC 2014-03-12 CN claimed
CN-100528865-C Imidazolo-5-yl-anilinopyrimidines as agents for the inhibition of cell proliferation ASTRAZENECA AB (SE) 2009-08-19 CN claimed
CN-1938295-A Imidazol-5-yl-anilinopyrimidines as cell proliferation inhibitors ASTRAZENECA AB (SE) 2007-03-28 CN claimed
EP-0175363-B1 4,5-DIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1990-01-17 EP claimed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP claimed
US-20200216496-A1 Antibacterial Compounds Produced by the Microorganism Strain Corallococcus Coralloides ST201330 (DSM 24989) SANOFI (FR) 2020-07-09 US disclosed
CN-106061977-A 1, 2-dihydro-3H-pyrrolo [1,2-C ] imidazol-3-one derivatives and their use as antibacterial agents 埃科特莱茵药品有限公司 2016-10-26 CN disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-101675053-B Phosphoinositide 3-kinase inhibitor compounds and methods of use GENENTECH INC 2014-03-12 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8324204-B2 Fused thiophene derivatives as kinase inhibitors UCB PHARMA SA (BE) 2012-12-04 US disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
CN-1094043-A Quinazoline derivant ZENECA LTD (GB) 1994-10-26 CN disclosed
EP-0175363-B1 4,5-DIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1990-01-17 EP disclosed
CN-1033628-A Imidazopyridine compound and preparation method thereof FUJISAWA PHARMACEUTIAL CO LTD (JP) 1989-07-05 CN disclosed
US-4816454-A CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-28 US disclosed
US-4816454-A CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-28 US disclosed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP disclosed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP disclosed