Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753345 | 0.93 | BTK (0.43) | BTKCLK2 | |
| SCHEMBL3749975 | 0.90 | BTK (0.41) | BTKCLK2 | |
| SCHEMBL3745143 | 0.90 | BTK (0.41) | BTKCLK2 | |
| SCHEMBL3757127 | 0.88 | BTK (0.44) | BTK | |
| SCHEMBL3747925 | 0.88 | BTK (0.42) | BTK | |
| SCHEMBL3739944 | 0.87 | BTK (0.42) | BTK | |
| SCHEMBL3744921 | 0.87 | BTK (0.43) | BTKCLK2 | |
| SCHEMBL3747910 | 0.83 | BTK (0.46) | BTK | |
| SCHEMBL3753351 | 0.82 | BTK (0.43) | BTK | |
| SCHEMBL1039925 | 0.82 | BTK (0.67) | BTKCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838523-B2 | Certain substituted amides, method of making, and method of use thereof | CGI PHARMACEUTICALS, INC. (US) | 2010-11-23 | — | — | US | disclosed |
| US-20080153834-A1 | Certain Substituted Amides, Method of Making, and Method of Use Thereof | GILEAD CONNECTICUT, INC. | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153834-A1 | Certain Substituted Amides, Method of Making, and Method of Use Thereof | BTK, SYK, MYD88 | BTK 1/4885CLK2 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.