SCHEMBL3757631

SCHEMBL3757631

CO/N=C(/C(=O)OC)c1ccccc1CON=C(C)c1ccc(C=C(F)Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.53
S1PR1 P21453 4/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3757516 0.92 HIF1A (0.55) HIF1AS1PR1NPC1RAB9AHPGD
SCHEMBL16440123 0.92 HIF1A (0.57) HIF1AS1PR1NPC1RAB9APPARG
SCHEMBL3758197 0.92 HIF1A (0.57) HIF1AS1PR1NPC1RAB9APPARG
SCHEMBL3752470 0.91 HIF1A (0.43) HIF1AS1PR1NPC1RAB9APPARG
SCHEMBL3758020 0.90 HIF1A (0.53) HIF1AS1PR1NPC1RAB9APPARG
SCHEMBL3759887 0.90 HIF1A (0.60) HIF1AS1PR1NPC1RAB9APPARG
SCHEMBL3746823 0.88 HIF1A (0.55) HIF1AS1PR1NPC1RAB9AHPGD
SCHEMBL23972091 0.87 HIF1A (0.67) HIF1AS1PR1NPC1RAB9AHPGD
SCHEMBL23972094 0.85 HIF1A (0.60) HIF1AS1PR1NPC1RAB9APPARG
SCHEMBL7558159 0.84 HIF1A (0.67) HIF1AS1PR1NPC1RAB9APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885S1PR1 3069/4885NPC1 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.