Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756204 | 0.86 | EGLN3 (0.54) | EGLN3EGLN1VEGFAFLT1 | |
| SCHEMBL3760876 | 0.85 | EGLN3 (0.54) | EGLN3KDM4EEGLN1VEGFAFLT1 | |
| SCHEMBL3752845 | 0.83 | EGLN3 (0.42) | EGLN3KDM4ESMN1; SMN2EGLN1VEGFA | |
| SCHEMBL3520006 | 0.77 | EGLN3 (0.43) | EGLN3KDM4EGRIN2BEGLN1VEGFA | |
| SCHEMBL3521397 | 0.77 | EGLN3 (0.46) | EGLN3KDM4ECYP17A1CYP21A2CYP11B1 | |
| SCHEMBL3521029 | 0.76 | EGLN3 (0.48) | EGLN3KDM4ECYP17A1CYP21A2CYP11B1 | |
| SCHEMBL3520873 | 0.74 | EGLN3 (0.40) | EGLN3KDM4EEGLN1VEGFAFLT1 | |
| SCHEMBL3761040 | 0.73 | HPGD (0.45) | EGLN3KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3519403 | 0.73 | EGLN3 (0.40) | EGLN3KDM4EGRIN2BSMN1; SMN2EGLN1 | |
| SCHEMBL3534707 | 0.73 | EGLN3 (0.41) | EGLN3KDM4EEGLN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | EGLN3 2/4885KDM4E 214/4885GRIN2B 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.