Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199146 | 0.86 | ATM (0.48) | ATMIRAK4DHODHLMNATP53 | |
| SCHEMBL1450054 | 0.83 | ATM (0.42) | ATMIRAK4DHODH | |
| SCHEMBL13057261 | 0.81 | ATM (0.44) | ATMIRAK4DHODHLMNA | |
| SCHEMBL30753925 | 0.81 | ATM (0.44) | ATMIRAK4DHODH | |
| SCHEMBL169389 | 0.81 | ATM (0.44) | ATMIRAK4DHODH | |
| SCHEMBL28999700 | 0.81 | ATM (0.50) | ATMIRAK4LMNA | |
| SCHEMBL18117491 | 0.81 | ATM (0.53) | ATMIRAK4DHODHLMNATP53 | |
| SCHEMBL27716556 | 0.81 | ATM (0.46) | ATMIRAK4DHODHLMNATP53 | |
| SCHEMBL28348101 | 0.80 | ATM (0.49) | ATMIRAK4DHODHLMNA | |
| SCHEMBL12393703 | 0.80 | ATM (0.49) | ATMIRAK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771069-B1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-20080058389-A1 | Carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058389-A1 | Carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| EP-1771069-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2005074686-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058389-A1 | Carboxamides | CBR3, CBR1, H1-10 | ATM 3443/4885IRAK4 2189/4885DHODH 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.