Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000084 | 0.92 | TDP1 (0.56) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL29000086 | 0.92 | TDP1 (0.56) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL31329227 | 0.85 | TDP1 (0.50) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL12970634 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL156437 | 0.83 | TDP1 (0.50) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL288562 | 0.83 | TDP1 (0.50) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL28629258 | 0.82 | APP (0.47) | ALDH1A1LMNAMAPK1CYP3A4TSHR | |
| SCHEMBL28414558 | 0.81 | CCNC (0.46) | ALDH1A1LMNACYP3A4CA2L3MBTL1 | |
| SCHEMBL10888642 | 0.80 | TDP1 (0.57) | TDP1ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL28084501 | 0.80 | TSHR (0.59) | TDP1ALDH1A1LMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310617-A1 | WATER-IN-OIL EMULSION SYSTEM AND PREPARATION PROCESS THEREOF | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310617-A1 | WATER-IN-OIL EMULSION SYSTEM AND PREPARATION PROCESS THEREOF | FAM83E, WDR12, WDR82 | TDP1 2115/4885ALDH1A1 4812/4885LMNA 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.