⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267145 | 1.00 | — | — | |
| SCHEMBL21473 | 1.00 | — | — | |
| SCHEMBL6271848 | 0.86 | — | — | |
| SCHEMBL7433871 | 0.84 | CRBN (0.34) | — | |
| SCHEMBL7428318 | 0.82 | KMT2A (0.34) | — | |
| SCHEMBL7433746 | 0.82 | KMT2A (0.34) | — | |
| SCHEMBL7430825 | 0.82 | KMT2A (0.34) | — | |
| SCHEMBL21693765 | 0.78 | — | — | |
| SCHEMBL10820878 | 0.78 | — | — | |
| SCHEMBL6442975 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1784220-A | Use of effectors of glutaminyl and glutamate cyclases | PROBIODRUG AG (DE) | 2006-06-07 | — | — | CN | claimed |
| EP-1620082-A2 | MEDICAL USE OF INHIBITORS OF GLUTAMINYL AND GLUTAMATE CYCLASES | Probiodrug AG (DE) | 2006-02-01 | — | — | EP | claimed |
| US-20050058635-A1 | Anticancer agents; therapy for infections; administering glutaminyl cyclase inhibitor; Alzheimer's disease; Down syndrome; controlling fertility; schizophrenia; skin disorders | PROBIODRUG AG (DE) | 2005-03-17 | — | — | US | claimed |
| WO-2004098625-A2 | MEDICAL USE OF INHIBITORS OF GLUTAMINYL AND GLUTAMATE CYCLASES | PROBIODRUG AG (DE) | 2004-11-18 | — | — | WO | claimed |
| EP-1063235-B1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LTD (JP) | 2004-05-12 | — | — | EP | claimed |
| US-20030186976-A1 | Benzofurylpyrone derivatives | TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2003-10-02 | — | — | US | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | claimed |
| EP-0406119-B1 | New peptide derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-01-19 | — | — | EP | claimed |
| US-5098888-A | Cholinergic agents and antispasmodic agents | ADIR ET COMPAGNIE (FR) | 1992-03-24 | — | — | US | claimed |
| EP-0099057-B1 | N-ACYL DERIVATIVES OF PEPTIDES, THEIR MANUFACTURE AND USE IN COMBATING DISEASES AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | claimed |
| EP-0233155-A1 | Aminoacyloxymethyl compounds | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | claimed |
| EP-0201459-A1 | Acylaminomethyl-penem compounds, their preparation and pharmaceutical formulations containing them | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | claimed |
| EP-0099057-A2 | N-acyl derivatives of peptides, their manufacture and use in combating diseases and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | claimed |
| US-12042541-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| EP-3757090-B1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORP (CA) | 2024-06-12 | — | — | EP | disclosed |
| EP-0027260-A2 | Peptides, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-22 | — | — | EP | disclosed |
| EP-0025842-A2 | Peptides, process for their preparation, their pharmaceutical compositions and their intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-01 | — | — | EP | disclosed |