Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162641 | 0.79 | HTR2C (0.50) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL23676966 | 0.74 | HTR2C (0.61) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL4077148 | 0.72 | SLC5A2 (0.52) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10078467 | 0.72 | EPHX1 (0.38) | HTR2BCYP2C19 | |
| SCHEMBL7784267 | 0.70 | HTR2C (0.54) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL746723 | 0.70 | HTR2C (0.49) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL6493903 | 0.70 | HTR2C (0.54) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL936624 | 0.70 | HTR2C (0.54) | HTR2CMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10078444 | 0.70 | SLC6A4 (0.42) | HTR2CKDM4EHTR2BCYP3A4CYP2D6 | |
| SCHEMBL9692360 | 0.70 | TSHR (0.51) | HTR2CMEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217184-B2 | Process for producing optically active cis-silyl olefin oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-8217184-B2 | Process for producing optically active cis-silyl olefin oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100305338-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CIS-SILYL OLEFIN OXIDE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| US-20100305338-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CIS-SILYL OLEFIN OXIDE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305338-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CIS-SILYL OLEFIN OXIDE COMPOUND | CYP51A1, MSMO1, SQLE | HTR2C 4212/4885MEN1 2050/4885KMT2A 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.