Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 13/20 | 0.40 |
| ▸ | EGFR | P00533 | 8/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3541445 | 1.00 | SOS1 (0.40) | SOS1EGFRERBB2KRAS | |
| SCHEMBL3769823 | 0.94 | EGFR (0.39) | SOS1EGFRERBB2KRAS | |
| SCHEMBL3769825 | 0.94 | EGFR (0.39) | SOS1EGFRERBB2KRAS | |
| SCHEMBL3769044 | 0.92 | EGFR (0.39) | SOS1EGFRERBB2KRAS | |
| SCHEMBL3536485 | 0.92 | EGFR (0.39) | SOS1EGFRERBB2KRAS | |
| SCHEMBL18010596 | 0.86 | EGFR (0.41) | SOS1EGFR | |
| SCHEMBL252518 | 0.82 | EGFR (0.44) | SOS1EGFRERBB2 | |
| SCHEMBL252517 | 0.82 | EGFR (0.44) | SOS1EGFRERBB2 | |
| SCHEMBL3544316 | 0.81 | EGFR (0.55) | EGFRERBB2 | |
| SCHEMBL232622 | 0.78 | EGFR (0.54) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8919342-B2 | Inhaler | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20100313886-A1 | INHALER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |