SCHEMBL3763

SCHEMBL3763

O=c1cc[nH]c(=O)n1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7650218 0.98 TP53 (0.33)
Hydrochloric Acid SCHEMBL27558760 0.98 KMT2A (0.33)
SCHEMBL27572393 0.98 BRD4 (0.31)
Water SCHEMBL28246131 0.98 BRD4 (0.31)
Ammonia Solution, Strong SCHEMBL28255127 0.98 BRD4 (0.31)
Fluoride SCHEMBL27679532 0.98 BRD4 (0.31)
Hydrochloric Acid SCHEMBL28839646 0.95 BRD4 (0.31)
Benzene SCHEMBL26606838 0.95 MAPK8 (0.36)
Water SCHEMBL27758775 0.95 BRD4 (0.31)
Hno SCHEMBL27940461 0.95 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 133095 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747263-A1 LIPID NANOPARTICLES AND USES THEREOF University of Connecticut (US) 2026-05-27 EP claimed
CN-122075677-A GM-CSF loaded tumor cell vaccine and application thereof in preventing and treating liver cancer 2026-05-26 CN claimed
US-20260139321-A1 METHODS FOR SEQUENCING SAMPLES AQTUAL INC (US) 2026-05-21 US claimed
US-20260137678-A1 METHODS FOR TREATING OR PREVENTING NEUROENDOCRINE TUMOR FORMATION USING XPO1 INHIBITORS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2026-05-21 US claimed
WO-2026102563-A1 DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2026-05-21 WO claimed
US-20260137700-A1 PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE SK BIOPHARMACEUTICALS CO LTD (KR) 2026-05-21 US claimed
WO-2026105121-A1 ANTICANCER FORMULATIONS AND USES THEREOF INTRAGEL THERAPEUTICS LTD. (IL) 2026-05-21 WO claimed
US-20260137674-A1 COMBINATION THERAPY USING A KRAS G12D INHIBITOR, AND A NUCLEOSIDE ANALOG, AND/OR A MICROTUBULE INHIBITOR INCYTE CORP (US) 2026-05-21 US claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
US-4671958-A Antibody conjugates for the delivery of compounds to target sites CYTOGEN CORPORATION (US) 1987-06-09 US claimed
EP-0213552-A2 Oily suspension for intrarectal infusion FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-03-11 EP claimed
CN-85104201-A From uridylic acid produce 5-fluoro-2 '-method of deoxyuridine 1986-11-26 CN claimed
CN-85108855-A The preparation method of 1-(2-tetrahydrofuran base)-5 FU 5 fluorouracil 1986-09-24 CN claimed
CN-85107905-A The preparation of uridine 1986-07-16 CN claimed
US-4565806-A Composition and method for rational treatment of cancer SETAELAE KAI M E 1986-01-21 US claimed
EP-0120907-A1 PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY Aston Molecules Limited (GB) 1984-10-10 EP claimed
WO-1984001506-A1 PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY UNIV BIRMINGHAM (GB) 1984-04-26 WO claimed
EP-0010964-A1 Ravidomycin, process of preparation and pharmaceutical compositions containing same AYERST, MCKENNA AND HARRISON INC. (CA) 1980-05-14 EP claimed
US-3992208-A Photo-sensitive etchant and method for forming metal image using same FUJI PHOTO FILM CO., LTD. (JA) 1976-11-16 US claimed