SCHEMBL3763382

SCHEMBL3763382

CNC(=O)/C(=N/OC)c1ccccc1CON=C(C)c1ccc(C=C(Cl)Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.46
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
S1PR1 P21453 4/20 0.33
PTGS2 P35354 1/20 0.33
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3755357 0.93 HIF1A (0.43) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL3752470 0.93 HIF1A (0.43) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL3759692 0.91 HIF1A (0.52) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL3759634 0.90 HIF1A (0.44) HIF1ANPC1RAB9AS1PR1HPGD
SCHEMBL3753794 0.90 HIF1A (0.44) HIF1ANPC1RAB9AS1PR1HPGD
SCHEMBL3758197 0.90 HIF1A (0.57) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL16440123 0.90 HIF1A (0.57) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL23972134 0.87 HIF1A (0.48) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL30354027 0.87 HIF1A (0.48) HIF1ANPC1RAB9APPARGPPARA
SCHEMBL23971823 0.87 HIF1A (0.53) HIF1ANPC1RAB9APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885NPC1 2127/4885RAB9A 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.