SCHEMBL376374

SCHEMBL376374

Cc1ccc(C=C(O)[C@H](O)[C@@H](O)[C@H](O)CO)cc1C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.34
▸ MAPK1 P28482 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ TUBB1 Q9H4B7 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28385425 1.00 MAPT (0.34) MAPTMAPK1MEN1LMNAKMT2A
SCHEMBL177517 0.95 PDE4A (0.36) MAPTMAPK1MEN1LMNAKMT2A
SCHEMBL20505218 0.95 PDE4A (0.36) MAPTMAPK1MEN1LMNAKMT2A
Water SCHEMBL28585861 0.93 PDE4A (0.34) MAPTMAPK1MEN1LMNAKMT2A
SCHEMBL27476451 0.88 CYP3A4 (0.35) MAPTMAPK1MEN1LMNAKMT2A
SCHEMBL376118 0.88 CYP3A4 (0.35) MAPTMAPK1MEN1LMNAKMT2A
SCHEMBL7117533 0.87 TUBB1 (0.37) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL29373037 0.87 TUBB1 (0.37) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL20599343 0.87 TUBB1 (0.37) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL34956 0.87 TUBB1 (0.37) MAPTMEN1LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408893-B1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES PROCTER & GAMBLE (US) 2013-04-17 — — EP claimed
US-8293697-B2 Structured fluid detergent compositions comprising dibenzylidene sorbitol acetal derivatives THE PROCTER & GAMBLE COMPANY (US) 2012-10-23 — — US claimed
US-8153574-B2 Structured fluid detergent compositions comprising dibenzylidene polyol acetal derivatives and detersive enzymes THE PROCTER & GAMBLE COMPANY (US) 2012-04-10 — — US claimed
EP-2408892-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE SORBITOL ACETAL DERIVATIVES The Procter & Gamble Company (US) 2012-01-25 — — EP claimed
EP-2408893-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES The Procter & Gamble Company (US) 2012-01-25 — — EP claimed
US-20100240571-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES PROCTER & GAMBLE COMPANY, THE 2010-09-23 — — US claimed
US-20100240569-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE SORBITOL ACETAL DERIVATIVES PROCTER & GAMBLE COMPANY, THE 2010-09-23 — — US claimed
WO-2010108000-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES THE PROCTER & GAMBLE COMPANY (US) 2010-09-23 — — WO claimed
WO-2010108002-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE SORBITOL ACETAL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2010-09-23 — — WO claimed
EP-2408893-B1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES PROCTER & GAMBLE (US) 2013-04-17 — — EP disclosed
US-8293697-B2 Structured fluid detergent compositions comprising dibenzylidene sorbitol acetal derivatives THE PROCTER & GAMBLE COMPANY (US) 2012-10-23 — — US disclosed
US-8153574-B2 Structured fluid detergent compositions comprising dibenzylidene polyol acetal derivatives and detersive enzymes THE PROCTER & GAMBLE COMPANY (US) 2012-04-10 — — US disclosed
EP-2408892-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE SORBITOL ACETAL DERIVATIVES The Procter & Gamble Company (US) 2012-01-25 — — EP disclosed
EP-2408893-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES The Procter & Gamble Company (US) 2012-01-25 — — EP disclosed
US-20100240569-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE SORBITOL ACETAL DERIVATIVES PROCTER & GAMBLE COMPANY, THE 2010-09-23 — — US disclosed
US-20100240571-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES PROCTER & GAMBLE COMPANY, THE 2010-09-23 — — US disclosed
WO-2010108000-A1 STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES THE PROCTER & GAMBLE COMPANY (US) 2010-09-23 — — WO disclosed
EP-0945452-B1 SUGAR COMPOUNDS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, PROCESSES FOR THE PREPARATION OF THEM, AND GEL COMPOSITIONS NEW JAPAN CHEM CO LTD (JP) 2003-11-19 — — EP disclosed
US-6187842-B1 REACTING SORBITOL OR XYLITOL WITH BENZALDEHYE IN PRESENCE OF ACID CATALYST NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-02-13 — — US disclosed
EP-0945452-A1 SUGAR COMPOUNDS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, PROCESSES FOR THE PREPARATION OF THEM, AND GEL COMPOSITIONS NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-09-29 — — EP disclosed
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