SCHEMBL37638

SCHEMBL37638

CO[Si](OC)(OC)C(CCN)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.50
HTR2A P28223 2/20 0.42
ALDH1A1 P00352 1/20 0.41
SLC6A4 P31645 3/20 0.40
SLC6A3 Q01959 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
TAAR1 Q96RJ0 4/20 0.39
SLC6A2 P23975 3/20 0.38
KCNK2 O95069 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1C Q13936 1/20 0.36
RIPK1 Q13546 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28128615 0.98 HRH1 (0.48) HRH1HTR2AALDH1A1SLC6A4SLC6A3
SCHEMBL2367821 0.89 HRH1 (0.53) HRH1HTR2AALDH1A1SLC6A4SLC6A3
SCHEMBL28848140 0.88 HRH1 (0.47) HRH1HTR2ASLC6A4SLC6A3CYP1A2
SCHEMBL28198315 0.85 TAAR1 (0.47) HRH1HTR2ASLC6A4SLC6A3CYP1A2
SCHEMBL6709671 0.83 HRH1 (0.37) HRH1HTR2AALDH1A1SLC6A2
SCHEMBL2820240 0.83 AOC3 (0.40) HRH1HTR2AALDH1A1CYP1A2CYP3A4
SCHEMBL4324150 0.82 HRH1 (0.47) HRH1HTR2AALDH1A1SLC6A4SLC6A3
SCHEMBL6289778 0.82 HRH1 (0.47) HRH1HTR2AALDH1A1SLC6A4SLC6A3
SCHEMBL6915165 0.81 HRH1 (0.33) HRH1HTR2ATSHRTAAR1RIPK1
SCHEMBL9398039 0.80 POLB (0.40) HRH1HTR2AALDH1A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370597-A1 CROSSLINKABLE MASSES BASED ON ORGANYLOXY-GROUP-CONTAINING ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2024-05-22 EP claimed
CN-115090283-B Supported core-shell catalyst, preparation method thereof and application thereof in catalyzing cyclopentyl butyrolactone hydrogenation 浙江新化化工股份有限公司 2024-01-02 CN claimed
CN-116850989-A Solid core-shell catalyst and preparation method and application thereof 山东海科创新研究院有限公司 2023-10-10 CN claimed
CN-114672232-B Primer coating for assembled building sealant, preparation method and application 杭州之江新材料有限公司 2023-09-22 CN claimed
CN-113736266-B Double-component heat-conducting gel and preparation method and application thereof 广州集泰化工股份有限公司 2023-07-07 CN claimed
WO-2023072376-A1 CROSSLINKABLE MASSES BASED ON ORGANYLOXY-GROUP-CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2023-05-04 WO claimed
CN-115090283-A Supported core-shell catalyst, preparation method thereof and application thereof in catalyzing hydrogenation of cyclopentyl butyrolactone 浙江新化化工股份有限公司 2022-09-23 CN claimed
WO-2022013803-A1 ANTI-MICROBIAL COMPOSITION COMPRISING SILANE ENCAPSULATED CU-AG NANOPARTICLES AND PROCESS OF PREPARATION THEREOF SICORA TECHNOLOGIES PRIVATE LIMITED (IN) 2022-01-20 WO claimed
EP-3565857-A1 CROSS-LINKABLE MASSES BASED ON ORGANOPOLYSILOXANES COMPRISING ORGANYLOXY GROUPS Wacker Chemie AG (DE) 2019-11-13 EP claimed
CN-110312766-A coating composition, coating film and electromagnetic interference shielding composite material 株式会社LG化学 2019-10-08 CN claimed
WO-2009084849-A2 CHROME-FREE COATING COMPOSITIONS FOR SURFACE-TREATING STEEL SHEET INCLUDING CARBON NANOTUBE, METHODS FOR SURFACE-TREATING STEEL SHEET AND SURFACE-TREATED STEEL SHEETS USING THE SAME POSCO (KR) 2009-07-09 WO claimed
WO-2008046434-A1 INK JET PRINTING HEAD TELECOM ITALIA S.P.A. (IT) 2008-04-24 WO claimed
US-6855792-B2 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2005-02-15 US claimed
EP-1490427-A1 AMBIENT CURED COATINGS AND COATED RUBBER PRODUCTS THEREFROM Lord Corporation (US) 2004-12-29 EP claimed
WO-2004011536-A1 AMBIENT CURED COATINGS AND COATED RUBBER PRODUCTS THEREFROM LORD CORPORATION (US) 2004-02-05 WO claimed
US-6492482-B2 WEAR AND CHEMICAL RESISTANCE DEGUSS-HUELS AKTIENGESELLSCHAFT (DE) 2002-12-10 US claimed
US-20020103286-A1 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2002-08-01 US claimed
EP-1211273-A1 Crosslinker and heatcurable lacquers Degussa AG (DE) 2002-06-05 EP claimed
US-20020042471-A1 Nonaqueous, heat-curable two-component coating DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2002-04-11 US claimed
EP-1193278-A1 Non aqueous, heat curable, two component coating composition Degussa AG (DE) 2002-04-03 EP claimed