SCHEMBL3764447

SCHEMBL3764447

C=CC(=O)OC(C)CC(C)(C)CCC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.37
THRB P10828 2/20 0.32
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23494085 0.86 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
Acrylic Acid Ethyl Ester SCHEMBL28574510 0.83 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL9209455 0.81 TSHR (0.43) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL28014167 0.81 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL23494088 0.80 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL4655027 0.79 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28014880 0.78 TSHR (0.34) TSHRHPGD
SCHEMBL3764879 0.77 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL10611134 0.77 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL8619029 0.77 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11466213-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2022-10-11 US disclosed
US-11254874-B2 Liquid-crystalline medium and high-frequency components comprising same MERCK PATENT GMBH (DE) 2022-02-22 US disclosed
US-11208594-B2 Liquid-crystalline medium and high-frequency components comprising same MERCK PATENT GMBH (DE) 2021-12-28 US disclosed
CN-107636116-B Liquid-crystalline medium and high-frequency module comprising same 默克专利股份有限公司 2021-12-10 CN disclosed
CN-107109235-B Liquid-crystalline medium and high-frequency module comprising same 默克专利股份有限公司 2021-05-14 CN disclosed
CN-107109230-B Liquid-crystalline medium and high-frequency module comprising same 默克专利股份有限公司 2021-03-05 CN disclosed
EP-3303519-B1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2021-01-27 EP disclosed
EP-3529334-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-10-07 EP disclosed
WO-2020152206-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-07-30 WO disclosed
US-10711197-B2 Liquid-crystalline medium and high-frequency components comprising same MERCK PATENT GMBH (DE) 2020-07-14 US disclosed
WO-2015169425-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2015-11-12 WO disclosed
US-20120249928-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 US disclosed
US-8199291-B2 Liquid crystal display device having polymer-stabilized blue phase liquid crystal layer and transparent films FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-7843540-B2 Liquid crystal display device and electronic apparatus SEIKO EPSON CORPORATION (JP) 2010-11-30 US disclosed
US-20090322997-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-12-31 US disclosed
US-7639327-B2 Liquid crystal display and electronic apparatus having a quasi-isotropic liquid crystal material SEIKO EPSON CORPORATION (JP) 2009-12-29 US disclosed
US-20080316403-A1 Liquid crystal display and electronic apparatus SEIKO EPSON CORPORATION (JP) 2008-12-25 US disclosed
US-7420635-B2 Liquid crystal display and electronic apparatus having a quasi-isotropic liquid crystal material SEIKO EPSON CORPORATION (JP) 2008-09-02 US disclosed
US-20060203169-A1 Liquid crystal display device and electronic apparatus SEIKO EPSON CORPORATION (JP) 2006-09-14 US disclosed
US-20060170846-A1 Liquid crystal display and electronic apparatus SEIKO EPSON CORPORATION (JP) 2006-08-03 US disclosed