Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324683 | 0.80 | TAAR1 (0.45) | TAAR1DPP4DPP7DPP8DPP9 | |
| SCHEMBL27725768 | 0.80 | CHRM2 (0.54) | TAAR1CHRM2 | |
| SCHEMBL7211808 | 0.78 | TAAR1 (0.52) | TAAR1DPP4DPP7CHRM2DPP8 | |
| SCHEMBL4708624 | 0.78 | TAAR1 (0.52) | TAAR1DPP4DPP7CHRM2DPP8 | |
| SCHEMBL8629574 | 0.75 | EPHX1 (0.59) | TAAR1MMP2SLC6A2SLC6A4 | |
| SCHEMBL8639910 | 0.75 | EPHX1 (0.59) | TAAR1MMP2SLC6A2SLC6A4 | |
| SCHEMBL16429484 | 0.75 | EPHX1 (0.59) | TAAR1MMP2SLC6A2SLC6A4 | |
| SCHEMBL16429100 | 0.75 | EPHX1 (0.59) | TAAR1MMP2SLC6A2SLC6A4 | |
| SCHEMBL23420598 | 0.74 | HTR2A (0.50) | TAAR1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8500978 | 0.74 | TAAR1 (0.69) | TAAR1CHRM2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851530-B2 | High viscosity at low shear; for use as sag control agents in coatings, paints, cosmetics, mining, paper, textile industries; Urea reaction product of isocyanate such as hexamethylene diisocyanate with high enantiomeric excess of optically active methylamines such as alpha-methylbenzylamine | NUPLEX RESINS B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-20060289828-A1 | Carbon-substituted methyl amine derivatives and their use as a rheology control agents | ALLNEX NETHERLANDS B.V. (NL) | 2006-12-28 | — | — | US | disclosed |