Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480778 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL2483259 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL5362558 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL1304140 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL1527497 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL2481162 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL181712 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL1850039 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL17780845 | 0.83 | TSHR (0.59) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL3759291 | 0.82 | TSHR (0.50) | TSHRTHRBPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305327-A1 | NITROXYL COMPOUND, AND POLYMERIZATION INHIBITOR AND POLYMERIZATION INHIBITOR COMPOSITION USING SAME | ADEKA CORPORATION (JP) | 2010-12-02 | — | — | US | disclosed |
| EP-1978017-A1 | NITROXYL COMPOUND, AND POLYMERIZATION INHIBITOR AND POLYMERIZATION INHIBITOR COMPOSITION USING SAME | Adeka Corporation (JP) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305327-A1 | NITROXYL COMPOUND, AND POLYMERIZATION INHIBITOR AND POLYMERIZATION INHIBITOR COMPOSITION USING SAME | NOX5, NOX1, NOC2L | TSHR 4881/4885THRB 4747/4885PRSS1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.