Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Micafungin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 1.00 |
| ▸ | PGR | P06401 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
| ▸ | UBE2M | P61081 | 1/20 | 1.00 |
| ▸ | NEDD8 | Q15843 | 1/20 | 1.00 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Micafungin SCHEMBL31615511 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL13575751 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL16550435 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL19600986 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL1652133 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL23001458 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL14380016 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL14403608 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL14071559 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL11893279 | 1.00 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10320 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124224-A1 | USE OF COMBINED COMPOSITION IN PREPARING DRUG FOR RESISTING FUNGAL AND BACTERIAL INFECTIONS | NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY (CN) | 2026-05-07 | — | — | US | claimed |
| US-20260124148-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | BHAMIS RES LABORATORY PVT LTD (IN) | 2026-05-07 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4729525-A1 | NEWLY SYNTHESIZED BORON-NITROGEN HETEROCYCLES AND THEIR CONJUGATES WITH PHARMACEUTICALLY UTILIZABLE SUBSTANCES | Julius-Maximilians-Universität Würzburg (DE) | 2026-04-22 | — | — | EP | claimed |
| US-20260102419-A1 | USE OF COMPOUNDS IN THE TREATMENT OF FUNGAL INFECTIONS | BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) | 2026-04-16 | — | — | US | claimed |
| EP-4719384-A2 | COMPOUNDS WITH ANTIFUNGAL PROPERTIES | Trustees of Dartmouth College (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4694908-A1 | GASTROINTESTINAL RETENTIVE FORMULATIONS OF ECHINOCANDINS | The Cleveland Clinic Foundation (US) | 2026-02-18 | — | — | EP | claimed |
| US-12534571-B2 | Amphiphilic block copolymer, preparation method thereof and nanomicelle drug-loading system | SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) | 2026-01-27 | — | — | US | claimed |
| US-12533321-B2 | Polypeptide formulations for oral delivery | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2026-01-27 | — | — | US | claimed |
| EP-4680240-A1 | METHOD OF TREATING DISORDERS WITH SURF1 MALFUNCTION | Cure Mito Foundation (US) | 2026-01-21 | — | — | EP | claimed |
| WO-2005007139-A2 | MULTIPARTICLE PHARMACEUTICAL DOSAGE FORM CONTAINING A MUCOADHESIVELY FORMULATED PEPTIDE OR PROTEIN ACTIVE SUBSTANCES METHOD FOR PRODUCING SAID PHARMACEUTICAL DOSAGE FORM | Röhm GmbH & Co. KG (DE) | 2005-01-27 | — | — | WO | claimed |
| US-20050013854-A1 | Introducing cargo moiety to liposome in solvent causing association then precipitating; efficient, easy scaled up | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-01-20 | — | — | US | claimed |
| US-20050013836-A1 | Antimicrobial flush solutions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-01-20 | — | — | US | claimed |
| WO-2005000189-A2 | METHOD AND APPARATUS FOR EXTENDING FEEDING TUBE LONGEVITY | RIDER DEAN LOLLER (US) | 2005-01-06 | — | — | WO | claimed |
| WO-2004108091-A2 | ANTIMICROBIAL FLUSH SOLUTIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-12-16 | — | — | WO | claimed |
| US-20040254545-A1 | Method and apparatus for extending feeding tube longevity | RIDER DEAN LOLLER (US) | 2004-12-16 | — | — | US | claimed |
| WO-2004091578-A2 | NOVEL ENCOCHLEATION METHODS, COCHLEATES AND METHODS OF USE | BIODELIVERY SCIENCES INTERNATIONAL, INC. (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040157837-A1 | Combinations for the treatment of fungal infections | COMBINATORX INCORPORATED | 2004-08-12 | — | — | US | claimed |
| WO-2004042350-A2 | USING AMINES OR AMINO ACIDS AS MOBILE PHASE MODIFIERS IN CHROMATOGRAPHY | MERCK & CO., INC. (US) | 2004-05-21 | — | — | WO | claimed |
| WO-2004002430-A2 | COMBINATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS | COMBINATORX INCORPORATED (US) | 2004-01-08 | — | — | WO | claimed |