SCHEMBL376717

SCHEMBL376717

C=CC1(C)CC(=O)NC1=O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP19A1 P11511 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27992207 0.81 TSHR (0.37) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL18497846 0.79 TSHR (0.45) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL83878 0.67
SCHEMBL9823939 0.67 TSHR (0.57) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL3372656 0.67
SCHEMBL10575291 0.67 TSHR (0.38) TSHRNPSR1KDM4ELMNACYP2C19
Hydrogen Sulfide SCHEMBL9272629 0.65 TSHR (0.50) TSHRNPSR1KDM4ELMNACYP2C19
Hydrochloric Acid SCHEMBL5728953 0.65 TSHR (0.50) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL6810022 0.64 TSHR (0.44) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL18497847 0.64 TSHR (0.65) TSHRNPSR1KDM4ELMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1727853-B1 ANIONIC WATER-IN-WATER POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE ASHLAND LICENSING & INTELLECTU (US) 2011-08-03 EP claimed
CN-1954021-B Anionic water-in-water polymer dispersions, method for the production thereof and use thereof ASHLAND LICENSING & INTELLECTU 2010-05-26 CN claimed
US-7323510-B2 Method for the production of water-in-water polymer dispersions ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2008-01-29 US claimed
US-20070203290-A1 Anionic Water-In-Water Polymer Dispersion, Method For The Production Thereof And Its Use ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2007-08-30 US claimed
CN-1954021-A Anionic water-in-water polymer dispersions, method for the production thereof and use thereof ASHLAND LICENSING & INTELLECTU (US) 2007-04-25 CN claimed
EP-1353975-B1 METHOD FOR THE PRODUCTION OF WATER-IN-WATER POLYMER DISPERSIONS STOCKHAUSEN CHEM FAB GMBH (DE) 2006-01-11 EP claimed
CN-1224637-C Process for producing water-in-water polymer dispersion STOCKHAUSEN CHEM FAB GMBH (DE) 2005-10-26 CN claimed
CN-1479762-A Process for producing water-in-water polymer dispersion ʩ�п˺�ɭ��˾ 2004-03-03 CN claimed
US-20040034145-A1 Method for the production of water-in-water polymer dispersions SOLENIS TECHNOLOGIES, L.P. 2004-02-19 US claimed
WO-2000001757-A1 ACRYLIC POLYMERS IN SUBSTANTIALLY AQUEOUS SUSPENSIONS SNF S.A. (FR) 2000-01-13 WO claimed
EP-3036293-B1 METHOD FOR MANUFACTURING OF ORGANIC HOLLOW PARTICLES BASF SE (DE) 2024-01-17 EP disclosed
US-20230399473-A1 HIGH MOLECULAR WEIGHT POLYMERIC DISPERSIONS MANUFACTURED UNDER CONTROLLED ADIABATIC CONDITIONS SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) 2023-12-14 US disclosed
US-20230399446-A1 HIGH MOLECULAR WEIGHT POLYMERIC DISPERSIONS WITH METAL SCAVENGER SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) 2023-12-14 US disclosed
US-20230399445-A1 HIGH MOLECULAR WEIGHT POLYMERIC DISPERSIONS SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) 2023-12-14 US disclosed
EP-4289874-A1 HIGH MOLECULAR WEIGHT POLYMERIC DISPERSIONS WITH METAL SCAVENGER Solenis Technologies Cayman, L.P. (US) 2023-12-13 EP disclosed
CN-1211260-A Formaldehyde-free aqueous binders BASF AG (DE) 1999-03-17 CN disclosed
US-5840804-A Crosslinked water-soluble polymer dispersions ROEHM GMBH CHEMISCHE FABRIK (DE) 1998-11-24 US disclosed
US-5541252-A Method of manufacturing water-soluble polymer dispersions having high polymer content ROHM GMBH (DE) 1996-07-30 US disclosed
US-5480934-A PREPARED BY COPOLYNERIZING WATER SOLUBLE, HYDROPHOBIC AND AMPHIPHILIC MONOMERS IN AQUEOUS DISPERSION USING POLYMERIC DISPERSANT IN TWO STEPS ROEHM GMBH CHEMISCHE FABRIK (DE) 1996-01-02 US disclosed
US-5403883-A Water soluble polymer dispersions ROEHM GMBH CHEMISCHE FABRIK (DE) 1995-04-04 US disclosed