Ethane

Ethane

SCHEMBL3767932

CC.CN(C)c1ccc(C(=O)O)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.74
KMT2A Q03164 4/20 0.74
MEN1 O00255 3/20 0.74
POLB P06746 2/20 0.74
ALDH1A1 P00352 5/20 0.67
MAPT P10636 3/20 0.67
HPGD P15428 2/20 0.67
RAB9A P51151 4/20 0.63
TSHR P16473 3/20 0.57
TP53 P04637 1/20 0.57
TOP1 P11387 2/20 0.53
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK1 P28482 2/20 0.52
CYP3A4 P08684 1/20 0.52
HBB P68871 1/20 0.52
KDM4E B2RXH2 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33368 0.98 NPC1 (0.77) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL2271443 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL1552312 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
Hydrochloric Acid SCHEMBL1982376 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
Ammonia Solution, Strong SCHEMBL28138417 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL28360958 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL10626135 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL5306452 0.95 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
Methoxymethane SCHEMBL18579214 0.91 NPC1 (0.69) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL8849509 0.91 NPC1 (0.69) NPC1KMT2AMEN1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2002292-B1 CONFORMABLE RETROREFLECTIVE FILM STRUCTURE ORAFOL AMERICAS INC (US) 2014-05-14 EP disclosed
US-7771059-B2 Conformable retroreflective film structure REFLEXITE CORPORATION (US) 2010-08-10 US disclosed
US-7556387-B2 Conformable retroreflective film structure REFLEXITE CORPORATION (US) 2009-07-07 US disclosed
US-20090168178-A1 Conformable retroreflective film structure ORAFOL AMERICAS INC. 2009-07-02 US disclosed
EP-1994432-A4 FLAME RETARDANT RETROREFLECTIVE FILM STRUCTURE REFLEXITE CORP (US) 2009-06-24 EP disclosed
US-7503664-B2 Flame retardant retroreflective film structure REFLEXITE CORPORATION (US) 2009-03-17 US disclosed
EP-1994432-A2 FLAME RETARDANT RETROREFLECTIVE FILM STRUCTURE Reflexite Corporation (US) 2008-11-26 EP disclosed
US-20080198460-A1 Conformable retroreflective film structure REFLEXITE CORPORATION (US) 2008-08-21 US disclosed
US-7374297-B2 Conformable retroreflective film structure REFLEXITE CORPORATION (US) 2008-05-20 US disclosed
US-20070236795-A1 Conformable retroreflective film structure ORAFOL AMERICAS INC. 2007-10-11 US disclosed
WO-2007108971-A2 FLAME RETARDANT RETROREFLECTIVE FILM STRUCTURE REFLEXITE CORPORATION (US) 2007-09-27 WO disclosed
US-20070223092-A1 Flame retardant retroreflective film structure ORAFOL AMERICAS INC. 2007-09-27 US disclosed