Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.64 |
| ▸ | TXK | P42681 | 1/20 | 0.55 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.55 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589523 | 0.80 | SYK (0.65) | SYKTXKKARS1SLK | |
| SCHEMBL374186 | 0.79 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373638 | 0.76 | SYK (0.68) | SYKTXKKARS1SLK | |
| SCHEMBL14279985 | 0.74 | SYK (0.68) | SYKTXKKARS1SLK | |
| SCHEMBL373791 | 0.73 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL27764191 | 0.73 | SYK (0.80) | SYKTXKKARS1SLK | |
| SCHEMBL373789 | 0.72 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL376832 | 0.72 | SYK (0.62) | SYKTXKKARS1SLK | |
| SCHEMBL373907 | 0.72 | SYK (0.81) | SYKTXKKARS1SLK | |
| SCHEMBL3772545 | 0.72 | SYK (1.00) | SYKTXKKARS1SLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215092-B1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |