SCHEMBL3769158

SCHEMBL3769158

C=CCOC(=O)c1ccc(C=C)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.67
CYP3A4 P08684 1/20 0.55
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 2/20 0.47
TSHR P16473 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
APP P05067 1/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43
TAS1R3 Q7RTX0 2/20 0.42
TAS1R1 Q7RTX1 2/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175786 0.90 SNCA (0.67) SNCACYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL5539391 0.87 SNCA (0.65) SNCACYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL17386391 0.85 SNCA (0.61) SNCACYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL26810445 0.85 SNCA (0.49) SNCACYP3A4ALDH1A1TSHRMEN1
SCHEMBL461801 0.85 SNCA (0.61) SNCACYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL26417020 0.85 SNCA (0.49) SNCACYP3A4ALDH1A1TSHRMEN1
SCHEMBL29030403 0.83 SNCA (0.47) SNCACYP3A4ALDH1A1TSHRMEN1
SCHEMBL31182 0.83 SNCA (0.59) SNCACYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL175787 0.83 SNCA (0.59) SNCACYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL5675836 0.83 SNCA (0.59) SNCACYP3A4ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1783151-B1 MDI based prepolymers and lacquers with improved properties containing the same, process for their preparation and their use BAYER MATERIALSCIENCE AG (DE) 2009-05-13 EP claimed
EP-2043185-B1 HYDRAZINE SUPPLY DEVICE, FUEL CELL SYSTEM UTILIZING THE SAME, VEHICLE CARRYING THE FUEL CELL SYSTEM, AND METHOD OF SUPPLYING HYDRAZINE OTSUKA CHEMICAL CO LTD (JP) 2013-09-04 EP disclosed
US-20120121496-A1 METHOD FOR STORING A HYDRAZINE RESIN OTSUKA CHEMICAL CO., LTD. (JP) 2012-05-17 US disclosed
US-20090317670-A1 Hydrazine supply device, fuel cell system utilizing the same, vehicle carrying the fuel cell system, and method of supplying hydrazine OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-24 US disclosed
US-20090318662-A1 Hydrazine storage resin OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-24 US disclosed
EP-2042524-A1 HYDRAZINE STORAGE RESIN Otsuka Chemical Co., Ltd. (JP) 2009-04-01 EP disclosed
EP-2043185-A1 HYDRAZINE SUPPLY DEVICE, FUEL CELL SYSTEM UTILIZING THE SAME, VEHICLE CARRYING THE FUEL CELL SYSTEM, AND METHOD OF SUPPLYING HYDRAZINE Otsuka Chemical Co., Ltd. (JP) 2009-04-01 EP disclosed