SCHEMBL3769189

SCHEMBL3769189

CC/C=C/COc1cccc(NC)c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
AOC3 Q16853 1/20 0.39
SLC5A2 P31639 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37
THRB P10828 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
SYK P43405 1/20 0.35
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3659936 1.00 APP (0.50) APPAOC3SLC5A2GAAHTT
SCHEMBL3654739 0.88 APP (0.48) APPAOC3GAAHTTHSD17B10
SCHEMBL3771342 0.88 APP (0.48) APPAOC3GAAHTTHSD17B10
SCHEMBL3656853 0.85 APP (0.51) APPAOC3GAAHTTHSD17B10
SCHEMBL3772893 0.85 APP (0.51) APPAOC3GAAHTTHSD17B10
SCHEMBL3659366 0.85 APP (0.46) APPTHRBKMT2A
SCHEMBL3770949 0.85 APP (0.46) APPTHRBKMT2A
SCHEMBL3657456 0.84 APP (0.48) APPHTTHSD17B10THRBKMT2A
SCHEMBL3657457 0.84 APP (0.48) APPHTTHSD17B10THRBKMT2A
SCHEMBL17138220 0.84 AOC3 (0.47) APPAOC3SLC5A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885AOC3 349/4885SLC5A2 2872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.