SCHEMBL3769302

SCHEMBL3769302

O=C(O)c1cccc2c(Br)ccc(C(=O)O)c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.56
CYP1A2 P05177 1/20 0.50
NR4A1 P22736 1/20 0.48
NR4A2 P43354 1/20 0.48
NR4A3 Q92570 1/20 0.48
HSD17B10 Q99714 1/20 0.47
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
PARP1 P09874 1/20 0.45
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 1/20 0.44
TYMS P04818 1/20 0.43
CDC25B P30305 1/20 0.43
TP53 P04637 1/20 0.42
WDR5 P61964 1/20 0.41
LDHA P00338 1/20 0.40
TSHR P16473 1/20 0.39
KDM4E B2RXH2 2/20 0.39
FABP4 P15090 1/20 0.39
AKR1C3 P42330 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31337530 1.00 PRNP (0.56) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL11679114 0.92 PRNP (0.56) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL29531845 0.90 PRNP (0.54) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL17982451 0.90 PRNP (0.54) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL1133960 0.90 PRNP (0.47) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL29195206 0.89 HSD17B10 (0.53) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL4260223 0.87 CYP1A2 (0.50) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL2830679 0.83 NR4A1 (0.61) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL31401789 0.83 NR4A1 (0.61) PRNPCYP1A2NR4A1NR4A2NR4A3
SCHEMBL29904701 0.83 NR4A1 (0.61) PRNPCYP1A2NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4033986-A Process for the preparation of 4-bromo-1,8-naphthalic acid anhydride AMERICAN HOECHST CORPORATION (US) 1977-07-05 US claimed
CN-106478505-A A kind of two-photon GSH probe and its preparation and application 浙江工业大学 2017-03-08 CN disclosed
US-7846638-B2 Composition for forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-07 US disclosed
EP-1560070-B1 COMPOSITION FOR FORMING ANTIREFLECTION FILM FOR LITHOGRAPHY NISSAN CHEMICAL IND LTD (JP) 2009-12-30 EP disclosed
US-7425399-B2 Composition for forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-09-16 US disclosed
US-20080206680-A1 Composition for forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-08-28 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-20060290429-A1 Composition form forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-12-28 US disclosed
EP-1560070-A1 COMPOSITION FOR FORMING ANTIREFLECTION FILM FOR LITHOGRAPHY Nissan Chemical Industries, Ltd. (JP) 2005-08-03 EP disclosed
EP-1206456-B1 THERMOCHROMIC RYLENE DYES BASF AG (DE) 2004-11-17 EP disclosed
US-20040023159-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2004-02-05 US disclosed
US-6486319-B1 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
US-6307068-B1 TREATING OR IN PREVENTING CANCER. ADIR ET COMPAGNIE (FR) 2001-10-23 US disclosed
EP-0157022-A1 Process for the preparation of 4-chloro / 4-bromonaphthalic acid anhydrid RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-10-09 EP disclosed
US-4212813-A OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1980-07-15 US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US disclosed
US-3954810-A Process for the preparation of 4-bromonaphthalic acid anhydride HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed