Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 16/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.69 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7771743 | 0.92 | SLC6A4 (0.73) | SLC6A4SLC6A2CACNA2D1 | |
| SCHEMBL20292638 | 0.86 | CACNA2D1 (0.73) | SLC6A4SLC6A2CACNA2D1 | |
| SCHEMBL20292552 | 0.86 | CACNA2D1 (0.73) | SLC6A4SLC6A2CACNA2D1 | |
| Oxalic Acid SCHEMBL3521 | 0.85 | CACNA2D1 (0.52) | SLC6A4SLC6A2CACNA2D1 | |
| Oxalic Acid SCHEMBL2525 | 0.83 | SLC6A4 (0.64) | SLC6A4SLC6A2CACNA2D1 | |
| SCHEMBL2722680 | 0.83 | SLC6A4 (1.00) | SLC6A4SLC6A2 | |
| SCHEMBL14085606 | 0.82 | SLC6A4 (0.75) | SLC6A4SLC6A2CACNA2D1 | |
| SCHEMBL14085621 | 0.82 | SLC6A4 (0.75) | SLC6A4SLC6A2CACNA2D1 | |
| Hydrochloric Acid SCHEMBL4848278 | 0.81 | SLC6A2 (0.73) | SLC6A4SLC6A2CACNA2D1 | |
| Hydrochloric Acid SCHEMBL4851048 | 0.81 | SLC6A2 (0.73) | SLC6A4SLC6A2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023269-A | 3-aryloxy-3-substituted propanamines | ELI LILLY AND COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0273658-B1 | 3-ARYLOXY-3-SUBSTITUTED PROPANAMINES | ELI LILLY AND COMPANY (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4956388-A | ANTIDEPRESSANTS, ANTIANXIETY, TREATMENT OF OBESITY, ADDICTION TO SMOKING AND ALCOHOL | ELI LILLY AND COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0273658-A1 | 3-Aryloxy-3-substituted propanamines | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |