Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.70 |
| ▸ | BCL2 | P10415 | 11/20 | 0.70 |
| ▸ | ALB | P02768 | 1/20 | 0.70 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376333 | 0.90 | BCL2L1 (0.86) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL377131 | 0.89 | BCL2L1 (0.88) | BCL2L1BCL2 | |
| SCHEMBL376331 | 0.87 | BCL2L1 (0.88) | BCL2L1BCL2 | |
| SCHEMBL376397 | 0.87 | BCL2L1 (0.88) | BCL2L1BCL2 | |
| SCHEMBL376454 | 0.87 | BCL2L1 (0.88) | BCL2L1BCL2 | |
| SCHEMBL376673 | 0.86 | BCL2L1 (0.80) | BCL2L1BCL2 | |
| SCHEMBL376581 | 0.85 | BCL2L1 (0.87) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL681276 | 0.82 | BCL2L1 (1.00) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL681275 | 0.82 | BCL2L1 (1.00) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL31384063 | 0.82 | BCL2L1 (1.00) | BCL2L1BCL2ALBBCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765778-B1 | N-SULFONYLCARBOXIMIDAMIDE APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2012-01-25 | — | — | EP | claimed |