Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 12/20 | 1.00 |
| ▸ | GRIN2B | Q13224 | 12/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390701 | 1.00 | GRIN1 (1.00) | GRIN1GRIN2BHRH3CYP2D6 | |
| SCHEMBL3390698 | 1.00 | GRIN1 (1.00) | GRIN1GRIN2BHRH3CYP2D6 | |
| SCHEMBL3395790 | 1.00 | GRIN1 (1.00) | GRIN1GRIN2BHRH3CYP2D6 | |
| SCHEMBL18587456 | 0.85 | GRIN2B (0.74) | GRIN1GRIN2B | |
| SCHEMBL3396820 | 0.85 | GRIN2B (0.74) | GRIN1GRIN2B | |
| SCHEMBL3394780 | 0.85 | GRIN2B (0.74) | GRIN1GRIN2B | |
| SCHEMBL3394777 | 0.85 | GRIN2B (0.74) | GRIN1GRIN2B | |
| SCHEMBL3392243 | 0.82 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL3394459 | 0.82 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL3392245 | 0.82 | GRIN1 (1.00) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122134-A1 | NR2B-SELECTIVE NMDA-RECEPTOR ANTAGONISTS | Westfälische Wilhelms Universität Münster (DE) | 2010-10-28 | — | — | WO | disclosed |